MITOCHONDRIAL DNA- REVOLUTIONARY EVOLUTION
نویسندگان
چکیده
منابع مشابه
Mitochondrial DNA evolution in mice.
This study extends knowledge of mitochondrial DNA (mtDNA) diversity in mice to include 208 animals belonging to eight species in the subgenus Mus. Highly purified mtDNA from each has been subjected to high-resolution restriction mapping with respect to the known sequence of one mouse mtDNA. Variation attributed to base substitutions was encountered at about 200 of the 300 cleavage sites examine...
متن کاملMitochondrial DNA and human evolution: A review
It was not until a few decades ago that research into evolution and anthropology could be broadened by molecular biology techniques, especially those, making use of the most detailed record of the life’s evolution – genetic material. A small fraction of a cell’s DNA is present in mitochondria, organelle involved in energy production. Higher mutation rate, different mode of inheritance, and the ...
متن کاملRapid concerted evolution in animal mitochondrial DNA.
Recombinational genetic processes are thought to be rare in the uniparentally inherited mitochondrial (mt) DNA molecules of vertebrates and other animals. Here, however, we document extremely rapid concerted microevolution, probably mediated by frequent gene conversion events, of duplicated sequences in the mtDNA control region of mangrove killifishes (Kryptolebias marmoratus). In local populat...
متن کاملMitochondrial DNA evolution in the genus Equus.
Employing mitochondrial DNA (mtDNA) restriction-endonuclease maps as the basis of comparison, we have investigated the evolutionary affinities of the seven species generally recognized as the genus Equus. Individual species' cleavage maps contained an average of 60 cleavage sites for 16 enzymes, of which 29 were invariant for all species. Based on an average divergence rate of 2%/Myr, the varia...
متن کاملMitochondrial DNA Mutations, Pathogenicity and Inheritance
Mitochondria contain their own DNA (mtDNA), which codes for 13 proteins (all subunits of the respiratory chain complexes), 22 tRNAs and 2 rRNAs. Several mtDNA point mutations as well as deletions have been shown to be causative in well-defined mitochondrial disorders. A mixture of mutated and wild type mtDNA (heteroplasmy) is found in most of these disorders. Inheritance of mtDNA is maternal, a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Evidence Based Medicine and Healthcare
سال: 2017
ISSN: 2349-2562,2349-2570
DOI: 10.18410/jebmh/2017/714